Pyrrole derivatives as alpha 7 NACHR modulators

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United States of America Patent

PATENT NO 9617210
APP PUB NO 20150344422A1
SERIAL NO

14655476

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Abstract

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Disclosed are compounds of the Formula (I), wherein R1, R2, R3, R4, R5, R6, R7 and m are as described herein, as modulators of the nicotinic acetylcholine receptors, particularly the α7 subtype, their tautomeric forms, stereoisomers, and their pharmaceutically acceptable salts, pharmaceutical compositions thereof, and combinations thereof with suitable other medicaments. Also disclosed are a process of preparation of the compounds and the intended uses thereof in therapy, particularly in the prophylaxis and/or treatment of disorders such as Alzheimer's disease, mild cognitive impairment, and senile dementia.

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Patent Owner(s)

Patent OwnerAddress
LUPIN LIMITED159 CST ROAD KALINA SANTACRUZ (EAST) MUMBAI 400 098

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Adurkar, Shridhar Keshav Pune, IN 4 6
Kamboj, Rajender Kumar Pune, IN 61 95
Karche, Navnath Popat Pune, IN 14 24
Palle, Venkata P Pune, IN 113 715
Sinha, Neelima Pune, IN 43 164

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