Oral sustained release pharmaceutical composition
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United States of America Patent
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Apr 11, 2017
Grant Date -
Nov 22, 2007
app pub date -
May 19, 2004
filing date -
May 20, 2003
priority date (Note) -
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Abstract
An oral sustained release pharmaceutical composition comprising a plurality of granules having diameters of not more than 1000 μm, wherein each of the granules comprise a nucleus granule comprised of beraprost sodium and a coating agent coating the nucleus granule, and wherein the coating agent is comprised of a first skin layer containing one or more relatively water-insoluble macromolecular substances, and a second skin layer containing one or more hot-melt low-melting substances.
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