Method of forming non-immunogenic hydrophobic protein nanoparticles, and uses therefor
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United States of America Patent
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Apr 11, 2017
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Oct 16, 2014
app pub date -
Mar 10, 2014
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May 9, 2008
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Abstract
Methods are described for producing non-immunogenic nanoparticles from protein sources by controlling the pH in a nanoprecipitation process. The nanoparticles that are produced by the disclosed methods range in diameter size from about 100 ran to about 400 nm, with a preferred diameter size of from approximately 100 nm to approximately 300 nm, thereby rendering them non-immunogenic. The invention further discloses methods for producing nanoconjugates that are suitable for a variety of therapeutic, diagnostic and other uses.
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