Biosynthetic pathway for heterologous expression of a nonribosomal peptide synthetase drug and analogs

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United States of America Patent

PATENT NO 9611491
APP PUB NO 20150050704A1
SERIAL NO

14467851

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Abstract

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The present invention is directed to the biosynthetic pathway for a nonribosomal peptide synthetase (NRPS) derived drug and analogs thereof. The invention also discloses polynucleotide sequences useful for heterologous expression in a convenient microbial host for the synthesis of the NRPS derived drug.

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Patent Owner(s)

Patent OwnerAddress
ALLEGHENY-SINGER RESEARCH INSTITUTE320 EAST NORTH AVENUE 10TH FLOOR SOUTH TOWER PITTSBURGH PA 15212

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ehrlich, Garth D Pittsburgh, US 8 34
Janto, Benjamin Pittsburgh, US 2 8
Rath, Christopher M San Diego, US 2 8
Sherman, David H Ann Arbor, US 37 53
Williams, Robert M Fort Collins, US 124 1770

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