Thermostable phytase variants

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United States of America Patent

PATENT NO 9611469
APP PUB NO 20150159149A1
SERIAL NO

14627584

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Abstract

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The present invention relates to a method for producing phytase variants which has at least 74% identity to a phytase derived from Citrobacter braakii and comprises at least two additional disulfide bonds as compared to this phytase. These phytase variants have modified, preferably improved, properties, such as thermostability, temperature profile, pH profile, specific activity, performance in animal feed, reduced protease sensitiliby, and/or an modified glycosylation pattern. The invention also relates to the variants produced, DNA encoding these phytases, methods of their production, as well as the use thereof, e.g., in animal feed and animal feed additives.

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NOVOZYMES A/SBAGSVAERD

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
De, Maria Leonardo Bagsvaerd, DK 64 154
Matsui, Tomoko Bagsvaerd, DK 72 408
Skov, Lars Kobberoee Bagsvaerd, DK 26 68

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges763281956782001332911183139501 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +050010001500200025003000350040004500500055006000650070007500800085009000

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11.5 Year Payment $7400.00 $3700.00 $1850.00 Oct 4, 2028