Methods and compositions related to a retinoid receptor-selective pathway
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United States of America Patent
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Apr 4, 2017
Grant Date -
Sep 24, 2015
app pub date -
May 6, 2011
filing date -
May 6, 2010
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Abstract
Provided herein are methods and compositions related to a retinoid receptor-selective pathway. As described herein, this pathway can be targeted to manipulate a tumor microenvironment. For example, the methods and compositions described herein can be used to induce apoptosis in a cancer cell. Further, the compositions described herein, including Sulindac and analogs thereof, can be used to target this pathway for the treatment or prevention of cancer in human patients.
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