Interfering peptides and method for detecting microorganisms
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United States of America Patent
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Mar 28, 2017
Grant Date -
Jan 22, 2015
app pub date -
Mar 11, 2013
filing date -
Mar 9, 2012
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Abstract
The invention relates to novel interfering peptides having peptide sequence S with between 7 and 12 amino acids, originating from the peptide sequence of an antigenic protein of a micro-organism M, the sequence S being aligned with a peptide sequence S′ with between 7 and 12 amino acids originating from the peptide sequence of a target protein of a micro-organism M′ that is different from the micro-organism M, provided that: sequences S and S′ have at least 50% identity over their length of 7 to 12 amino acids and at least 4 identical or analogous contiguous amino acids; and their length is identical or they have 1 or 2 different amino acids distributed at one and/or the other end of the sequences. The invention also relates to a method for the in vitro immunoassay-based detection of the presence of a micro-organism M′ or M in a biological sample.
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