gene and application thereof
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United States of America Patent
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Mar 28, 2017
Grant Date -
May 26, 2016
app pub date -
May 23, 2014
filing date -
May 24, 2013
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Abstract
The invention relates to the field of modifying E. coli through genetic engineering. Specifically, the invention provides an E. coli containing a mutated lpdA gene. The invention also relates to use of the E. coli in the production of chemical material such as ethanol, and succinate etc. The invention also provides a method of producing chemical materials such as ethanol and succinate etc. by using the E. coli, as well as a method for increasing the activity of pyruvate dehydrogenase in E. coli by introducing a mutated lpdA gene.
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