Humanized anti-IL-10 antibodies for the treatment of systemic lupus erythematosus (SLE)

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United States of America Patent

PATENT NO 9605066
APP PUB NO 20150064179A1
SERIAL NO

14473186

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Abstract

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Provided is a humanized or chimeric antibody or fragment thereof capable of binding to interleukin-10 (IL-10), wherein said antibody or fragment thereof is capable of being administered to a subject in the absence of an intolerable increase in the level of pro-inflammatory cytokines. Further provided are methods of treatment involving the use of the antibody or fragment thereof.

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Patent Owner(s)

Patent OwnerAddress
BIOTEST AG63303 DREIEICH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bruecher, Christoph Eschborn, DE 18 212
Czeloth, Niklas Dreieich, DE 7 49
Daelken, Benjamin Frankfurt am Main, DE 24 242
Engling, André Bad Homburg, DE 5 27
Gutscher, Marcus Langen, DE 5 8
Osterroth, Frank Dietzenbach, DE 18 201
Röttgen, Peter Ladenburg, DE 6 19
Uherek, Christoph Seligenstadt, DE 26 324
Wartenberg-Demand, Andrea Schrecksbach, DE 13 124
Wessels-Kranz, Judith Frankfurt am Main, DE 2 4
Zuber, Chantal Frankfurt am Main, DE 9 53

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