Antigen binding formats for use in therapeutic treatments or diagnostic assays

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United States of America Patent

PATENT NO 9598499
SERIAL NO

13976481

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Abstract

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The present invention relates to antigen binding formats for use in therapeutic treatments or diagnostic assays. The present invention relates to an antigen-binding format consisting of: —a first fusion protein wherein the CH1 constant domain of an antibody is fused i) by its N-terminal end to the C-terminal end of a variable domain of an antibody and ii) by its C-terminal end to the N-terminal end of a variable domain of an antibody and, —a second fusion protein wherein the CL constant domain of an antibody is fused by its N-terminal end to the C-terminal end of a variable domain of an antibody.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)101 RUE DE TOLBIAC PARIS 75013
UNIVERSITE D'AIX-MARSEILLEMARSEILLE
ASSISTANCE PUBLIQUE - HOPITAUX DE MARSEILLE80 RUE BROCHIER MARSEILLE 13005

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baty, Daniel Marseilles, FR 19 43
Chames, Patrick Marseilles, FR 30 498
Kerfelec, Brigitte Marseilles, FR 5 8
Mansais, Martine Marseilles, FR 3 6
Rozan, Caroline Marseilles, FR 3 2

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