Blockage of interferon-gamma for prevention of polymicrobial synergy
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United States of America Patent
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Mar 21, 2017
Grant Date -
May 5, 2011
app pub date -
Feb 2, 2009
filing date -
Feb 1, 2008
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Abstract
The present invention is directed to methods for treating a viral respiratory infection in a subject, preventing polymicrobial synergy in a subject, or preventing a bacterial infection in a subject. These methods include selecting a subject with a viral respiratory infection, a subject susceptible to polymicrobial synergy, or a subject susceptible to bacterial infection, respectively. In each case a therapeutic agent that inhibits interferon-gamma (IFNγ) is provided and administered to the selected subject under conditions effective to treat the viral respiratory infection, to prevent polymicrobial synergy, or to prevent a bacterial infection, respectively.
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