Substituted quinoline compounds and methods of use
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United States of America Patent
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Mar 21, 2017
Grant Date -
Dec 3, 2015
app pub date -
Aug 12, 2015
filing date -
Feb 28, 2011
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Abstract
The present invention provides novel substituted quinoline compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.
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