Chiral diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex

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United States of America Patent

PATENT NO 9598355
APP PUB NO 20150099636A1
SERIAL NO

14510603

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Abstract

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The present invention provides diacylhydrazine ligands and chiral diacylhydrazine ligands for use with ecdysone receptor-based inducible gene expression systems. Thus, the present invention is useful for applications such as gene therapy, large scale production of proteins and antibodies, cell-based screening assays, functional genomics, proteomics, metabolomics, and regulation of traits in transgenic organisms, where control of gene expression levels is desirable. An advantage of the present invention is that it provides a means to regulate gene expression and to tailor expression levels to suit the user's requirements.

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Patent Owner(s)

Patent OwnerAddress
INTREXON CORPORATIONBLACKSBURG VA 24060

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hormann, Robert Eugene Melrose Park, US 38 578
Li, Bing Shrewsbury, US 454 3928

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