Cyclic-dinucleotides and its conjugates as adjuvants and their uses in pharmaceutical compositions
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United States of America Patent
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Mar 21, 2017
Grant Date -
Nov 20, 2008
app pub date -
Nov 8, 2006
filing date -
Nov 8, 2005
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Abstract
The present invention relates to new adjuvants and the uses in pharmaceutical compositions, like in vaccines. In particular, the present invention provides new compounds useful as adjuvants and/or immunomodulators for prophylactic and/or therapeutic vaccination in the treatment of infectious diseases, inflammatory diseases, autoimmune diseases, tumors, allergies as well as for the control of fertility in human or animal populations. The compounds are particularly useful not only as systemic, but preferably as mucosal adjuvants. In addition, the invention relates to its uses as active ingredients in pharmaceutical compositions.
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