Humanization of rabbit antibodies using a universal antibody framework

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United States of America Patent

PATENT NO 9593161
SERIAL NO

14179141

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Abstract

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The present invention relates to an universal antibody acceptor framework and to methods for grafting non-human antibodies, e.g., rabbit antibodies, using a universal antibody acceptor framework. Antibodies generated by the methods of the invention are useful in a variety of diagnostic and therapeutic applications.

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Patent Owner(s)

Patent OwnerAddress
NOVARTIS AGLICHTSTRASSE 35 4056 BASEL 4056

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Borras, Leonardo Jose Schlieren, CH 11 99
Urech, David Hombrechtikon, CH 67 259

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