Process for the asymmetric hydrogenation of imides
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United States of America Patent
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Mar 14, 2017
Grant Date -
Jun 28, 2012
app pub date -
Jun 17, 2010
filing date -
Jun 19, 2009
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Abstract
The present disclosure provides a process for the mono-reduction of one or more imide moieties in a compound comprising contacting the compound with hydrogen gas and a catalyst comprising a transition metal hydride in the presence of a base, under conditions for the mono-reduction of the one or more imide moieties to form a compound comprising one or more hydroxy amides.
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