containing abundant amount of active ingredient, the preparation thereof, and the composition comprising the same as an active ingredient for preventing or treating inflammation, allergy and asthma

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9592263
APP PUB NO 20160199430A1
SERIAL NO

14653852

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Abstract

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A method for preparing purified extract containing more abundant active ingredients such as catalpol derivatives from the extract of Pseudolysimachion rotundum var subintegrum than that prepared by the conventional preparation method disclosed in the prior art and the therapeutics or functional health food comprising the purified extract for treating and preventing inflammatory, allergic or asthmatic disease. The purified extract showed more potent anti-inflammatory, anti-allergy and anti-asthma activity than that prepared by the conventional preparation method disclosed in the prior art through various in vivo tests such as inhibition test on the reproduction of eosinophil, the release of immunoglobulin and inflammatory chemokines in plasma and bronchoalveolar fluid as well as the suppression of airway hyperresponsiveness and goblet cell hyperplasia in a OVA-sensitized/challenged mouse model.

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Patent Owner(s)

  • KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY;YUNGJIN PHARMACEUTICAL CO., LTD.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ahn, Kyung-seop Daejeon, KR 6 0
Kim, Doo-young Daejeon, KR 40 133
Kim, Jung-hee Daejeon, KR 20 54
Kwon, Ok-kyoung Daejeon, KR 20 1
Lee, Hyeongkyu Daejeon, KR 6 0
Lee, Yongnam Suwon-si, KR 8 0
Oh, Sei-ryang Daejeon, KR 26 10
Ryoo, Byung-hwan Seongnam-si, KR 10 10
Shin, Dae-hee Seoul, KR 10 10
Song, Hyuk-hwan Daejeon, KR 9 7
Yoo, Ji-seok Suwon-si, KR 9 9

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