Methods of propagating monkey adenoviral vectors
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United States of America Patent
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Mar 7, 2017
Grant Date -
Nov 19, 2015
app pub date -
Aug 4, 2015
filing date -
Nov 9, 2009
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Abstract
The invention provides methods for propagating a monkey adenovirus in a cell, including a human cell, comprising one or more gene products isolated from a human adenovirus. Also provided are methods for propagating wherein the monkey adenovirus comprises a nucleic acid sequence encoding a human adenovirus gene product. The invention further provides a monkey adenovirus, including a replication-deficient monkey adenovirus, obtained by such propagation methods.
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