Quinazoline derivative as tyrosine-kinase inhibitor, preparation method therefor and application thereof

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United States of America Patent

PATENT NO 9586939
SERIAL NO

14119945

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Abstract

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The invention relates to a quinazoline derivative represented by the general formula (I), a pharmaceutical acceptable salt and a stereoisomer thereof as tyrosine kinase inhibitor, wherein R1, R2, R3, R3′, R4, R5, R6, X, L, T, Z and q are as defined in the specification. The invention also relates to a process for preparing the same, a pharmaceutical composition and a pharmaceutical formulation containing the derivative, use of the derivative for treating excessive proliferative diseases and chronic obstructive pulmonary disease and use of the derivative in the manufacture of a medicament for treating excessive proliferative diseases and chronic obstructive pulmonary disease.

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Patent Owner(s)

Patent OwnerAddress
XUANZHU PHARMA CO LTD2518 TIANCHEN STREET NATIONAL HIGH-TECH DEVELOPMENT ZONE JINAN-CITY SHANDONG PROVINCE 250101

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Wang, Aichen Jinan, CN 10 18
Wu, Frank Jinan, CN 101 2813

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