Triazolyl derivatives as Syk inhibitors

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United States of America Patent

PATENT NO 9586931
APP PUB NO 20150239866A1
SERIAL NO

14431895

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Abstract

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Provided are triazole derivatives of Formula I which are potent inhibitors of spleen tyrosine kinase and pharmaceutical composition. The triazole derivatives are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer.

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Patent Owner(s)

Patent OwnerAddress
MERCK SHARP & DOHME LLC126 EAST LINCOLN AVENUE RAHWAY NJ 07065

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Altman, Michael D Needham, US 65 795
Beaulieu, Christian Laval, CA 15 127
Cash, Brandon Framingham, US 8 60
Childers, Kaleen Konrad Medfield, US 14 203
Christopher, Matthew Brookline, US 20 172
Donofrio, Anthony Cambridge, US 23 225
Ducharme, Yves Brookline, US 34 1401
Ellis, John Michael Needham, US 23 252
Grimm, Jonathan Ashburn, US 13 156
Guay, Daniel Lachine, CA 52 1498
Haidle, Andrew M Cambridge, US 25 261
Kattar, Solomon D Arlington, US 21 250
Machacek, Michelle R Brookline, US 22 299
Northrup, Alan B Reading, US 41 468
O'Boyle, Brendan Milpitas, US 6 40
Otte, Ryan D Natick, US 34 321
Reutershan, Michael H Brookline, US 18 172
Romeo, Eric T Allston, US 6 58
Spencer, Kerrie Woonsocket, US 9 61
Vitharana, Dilrukshi Somerville, US 9 67
Wu, Lingyun Shanghai, CN 45 68
Zhang, Li Shanghai, CN 2775 40019
Zhang, Peng Shanghai, CN 846 8792

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