Crystalline anhydrous form of Cabazitaxel, process for the preparation and pharmaceutical compositions thereof

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United States of America Patent

PATENT NO 9586919
APP PUB NO 20160244420A1
SERIAL NO

15030620

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Abstract

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The present invention relates to a new anhydrous crystalline form of Cabazitaxel of formula (I), designated as form H. A further object of the present invention is a processes for the preparation of the above mentioned form H by recrystallization of Cabazitaxel from a mixture of decanoyl- and octanoyl triglycerides or from glycerol trioctanoate. Form H of Cabazitaxel is useful for the preparation of Cabazitaxel, Cabazitaxel salts, and polymorphic forms thereof. It is also particularly useful as a medicament, especially for the treatment of cancers.

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Patent Owner(s)

Patent OwnerAddress
INDENA S P A20139 MILANO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cabri, Walter Milan, IT 98 224
Ciceri, Daniele Milan, IT 15 7
Domenighini, Luca Milan, IT 3 4
Gambini, Andrea Milan, IT 14 37
Peterlongo, Federico Milan, IT 7 5

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