Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors

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United States of America Patent

PATENT NO 9586888
SERIAL NO

14149492

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Abstract

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Phenyl-substituted cyclohexylamine derivatives and method for their synthesis and characterization are disclosed. Use of these compounds to treat/prevent neurological disorders as well as methods for their synthesis are set forth herein. Exemplary compounds of the invention inhibit reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine (e.g., from the synaptic cleft) and modulate one or more monoamine transporter. Pharmaceutical formulations incorporating compounds of the invention are also provided.

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Patent Owner(s)

Patent OwnerAddress
SUNOVION PHARMACEUTICALS INC84 WATERFORD DRIVE MARLBOROUGH MA 01752

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Campbell, Una Marlborough, US 23 163
Engel, Sharon Rae Hudson, US 8 67
Hardy, Larry Wendell Sturbridge, US 18 81
Hewitt, Michael Charles Somerville, US 33 293
Koch, Patrick Marlborough, US 19 107
Ma, Jianguo Natick, US 63 707
Malcolm, Scott Christopher Southborough, US 8 67
Ribe, Seth Worcester, US 3 15
Schreiber, Rudy Watertown, US 19 222
Shao, Liming Lincoln, US 54 419
Spear, Kerry L Concord, US 51 500
Varney, Mark A Laguna Nigel, US 17 177
Wang, Fengjiang Northborough, US 27 275

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