Dyes and labeled molecules
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United States of America Patent
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Feb 28, 2017
Grant Date -
Apr 17, 2014
app pub date -
Aug 15, 2013
filing date -
Mar 17, 2005
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Abstract
Dimeric and trimeric nucleic acid dyes, and associated systems and methods are provided. Such a dye may form a hairpin-like structure that enables it to stain nucleic acids via a release-on-demand mechanism, for example. Such a dye may have low background fluorescence in the absence of nucleic acids and high fluorescence in the presence of nucleic acids, upon binding therewith, for example. A dye provided herein may be useful in a variety of applications, such as in DNA quantitation in real-time PCR, for example.
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