Retinal OFF circuit-specific promoter
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United States of America Patent
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Feb 28, 2017
Grant Date -
Dec 3, 2015
app pub date -
Aug 26, 2013
filing date -
Aug 27, 2012
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Abstract
The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 200 bp having at least 70% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in cones and/or OFF bipolar cells of a gene when operatively linked to a nucleic acid sequence coding for said gene.
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