Human monoclonal antibodies derived from human B cells and having neutralizing activity against influenza A viruses
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United States of America Patent
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Feb 21, 2017
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Jan 3, 2013
app pub date -
Mar 7, 2011
filing date -
Mar 8, 2010
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Abstract
The present invention relates to human monoclonal antibodies derived from human B cells present in the blood of patients who had recovered from infection with influenza A viruses, wherein the monoclonal antibodies have neutralizing activity against influenza A viruses. The anti-influenza A virus monoclonal antibody of the present invention has binding and neutralizing activities against at least one influenza A virus selected from the group consisting of influenza A virus H1, H2 and H5 subtypes, and thus it is useful for the prevention and treatment of a disease caused by the influenza A virus and is also useful for diagnosis of influenza A virus infection.
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