Process for the preparation of Dolutegravir

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United States of America Patent

PATENT NO 9573965
APP PUB NO 20160108058A1
SERIAL NO

14888702

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Abstract

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The present invention provides (R)-3-Amino-1-butanol (D)-tartarate (IIb); process for its preparation and its conversion to Dolutegravir. The present invention also provides an improved process for the preparation of Dolutegravir (I) or pharmaceutically acceptable salts wherein compound (XVI) is reacted with an optically active acid addition salt of (R)-3-amino-1-butanol (IIa).

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Patent Owner(s)

Patent OwnerAddress
AUROBINDO PHARMA LTDHYDARABAD

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Budidet, Shankar Reddy Hyderabad, IN 5 4
Danda, Subba Reddy Hyderabad, IN 4 20
Dussa, Nageshwar Hyderabad, IN 1 1
Kaki, Gowrisankar Rao Hyderabad, IN 2 3
Katuroju, Srinivasachary Hyderabad, IN 2 3
Meenakshisunderam, Sivakumaran Hyderabad, IN 78 111
Sanapureddy, Jagan Mohan Reddy Hyderabad, IN 4 2
Yatcherla, Srinivasa Rao Hyderabad, IN 2 3

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