Peptidyl arginine deiminase 1 and/or 3 activator compounds in the epidermis and uses thereof

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United States of America Patent

PATENT NO 9566222
APP PUB NO 20140030200A1
SERIAL NO

14110977

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Abstract

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The present invention relates to the activation of peptidyl arginine deiminase (PADs) 1 and/or 3 in the epidermis by at least one active agent used alone or in combination, namely caffeine, acefylline and/or theobromine in a cosmetic and/or pharmaceutical composition. The present invention also relates to the use of the aforementioned active agents in cosmetics and/or therapeutics, alone or in combination, in order to improve the barrier functions of the epidermis, to prevent and/or treat symptoms related to dry skin or to improve and/or promote hydration of the keratinous layer. Finally, the invention relates to increasing the activity of PAD1 and/or PAD3 in the epidermis.

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Patent Owner(s)

Patent OwnerAddress
PIERRE FABRE DERMO-COSMETIQUE92100 BOULOGNE-BILLANCOURT

International Classification(s)

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  • 2012 Application Filing Year
  • A61K Class
  • 11964 Applications Filed
  • 9694 Patents Issued To-Date
  • 81.03 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201220132014201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Daunes-Marion, Sylvie Toulouse, FR 12 8
Duplan, Hélène Auzeville Tolosane, FR 8 2
Mechin, Marie-Claire Lapeyrousse-Fossat, FR 2 1
Poigny, Stéphane Saubens, FR 19 7
Serre, Guy Toulouse, FR 15 42
Simon, Michel Belberaud, FR 18 68

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges763281956782001332911183139501 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +050010001500200025003000350040004500500055006000650070007500800085009000

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