Compositions and methods for inhibiting norovirus infection
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United States of America Patent
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Feb 7, 2017
Grant Date -
Jul 7, 2016
app pub date -
Mar 11, 2016
filing date -
Jul 12, 2013
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Abstract
A composition for use in inhibiting the binding of a Norovirus to the histo-blood group antigen on the surface of epithelia is disclosed. The composition may contain a therapeutically effective amount of a binding-inhibiting compound and a carrier and/or excipient. The compounds may competitively bind a Norovirus that has the capability of binding with the histo-blood group antigens of secretor blood type, including A, B, AB, and O blood types. The compositions may be administered to a human prior to or after infection by a Norovirus, to prevent, ameliorate, or reduce the effects of an infection.
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