Method of reducing cholesterol levels using a human anti-PCSK9 antibody
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United States of America Patent
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Feb 7, 2017
Grant Date -
Jun 5, 2014
app pub date -
Jan 27, 2012
filing date -
Jan 28, 2011
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Abstract
The present invention relates to methods for treating diseases or conditions in which proprotein convertase subtilisin/kexin type 9 (PCSK9) expression or activity causes an impact by administration of PCSK9-specific antibodies or antigen-binding fragments thereof and preferably by additional administration of an inhibitor of 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMG-CoA reductase). The present invention further relates to PCSK9-specific antibodies or antigen-binding fragments thereof for use in the treatment of diseases or conditions in which PCSK9 expression or activity causes an impact.
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