Regulation of epigenetic control of gene expression

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United States of America Patent

PATENT NO 9550990
APP PUB NO 20090298910A1
SERIAL NO

11721326

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods are provided for the identification of compounds that selectively modulate epigenetic changes in gene expression. Compounds, compositions, kits or assays devices, and methods are provided for modulating the expression, endogenous levels or the function of small non-coding RNAs cognate to or transcribed by heterochromatic regions subject to epigenetic regulation (i.e., promoters, enhancers, centromeres, telomeres, origins of DNA replication, imprinted loci, or loci marked by dosage-compensation), and for modulating the formation or function of heterochromatin in cells, tissues or animals.

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Patent Owner(s)

Patent OwnerAddress
ISIS PHARMACEUTICALS INC1896 RUTHERFORD ROAD CARLSBAD CA 92008

International Classification(s)

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  • 2005 Application Filing Year
  • C12N Class
  • 2871 Applications Filed
  • 1177 Patents Issued To-Date
  • 41 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances200520062007200820092010201120122013201420152016201720182019202020210255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Griffey, Richard H Vista, US 162 5753
Perera, Ranjan Carlsbad, US 16 106
Vickers, Timothy Oceanside, US 21 357

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  • C12N Class
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges2925224021854181131251101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0200400600800100012001400160018002000220024002600280030003200

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