Influenza virus immunizing epitope
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United States of America Patent
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Jan 17, 2017
Grant Date -
Aug 4, 2011
app pub date -
Jul 15, 2009
filing date -
Jul 18, 2008
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Abstract
A method for synthesizing influenza virus-like particles (VLPs) within a plant or a portion of a plant is provided. The method involves expression of a novel influenza HA protein in plants and its purification The invention is also directed towards a VLP comprising influenza HA protein and plants lipids. The invention is also directed to a nucleic acid encoding improved influenza HA as well as vectors. The VLPs may be used to formulate influenza vaccines, or may be used to enrich existing vaccines.
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