Compositions and methods for reducing background DNA amplification
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United States of America Patent
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Jan 17, 2017
Grant Date -
Dec 5, 2013
app pub date -
Mar 13, 2013
filing date -
Jun 4, 2012
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Abstract
Compositions are provided that include a plurality of small molecules selected from the group consisting of an amide, urea or acetone having a molecular weight less than 300 g/mol; and dNTPs and a polymerase in a buffer suitable for use as an amplification buffer. Methods of use of the compositions are also described for reducing non-template DNA amplification.
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