Complexes of germanium with amino acids and carboxylic acids and method for preparing same
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United States of America Patent
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Jan 17, 2017
Grant Date -
Jan 8, 2015
app pub date -
Nov 9, 2012
filing date -
Jan 25, 2012
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Abstract
The invention relates to complexes of germanium with amino acids and carboxylic acids of the general formula Ge[OH]a[AA]b[CA]c (I),
- where AA is an amino acid, CA is a carboxylic acid,a=0÷3, b=1÷3, c=0÷3, and 1≦b+c≦4, wherein AA and AC in the complex can be identical or different, and to a method for preparing same. The method consists in preparing an aqueous suspension of germanium dioxide, adding an amino acid and a carboxylic acid to the aqueous suspension of germanium oxide produced, heating the mixture produced with agitation at a temperature of 40-100° C. for 2-14 hours with subsequent filtering, removal of the water and production of a complex in solid form. The method makes it possible to prepare stable complexes with a controllable composition and a controllable ratio of germanium to amino acid and carboxylic acid which are stable in solid form and can be used in medicine.
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