Substituted quinazolin-4-ones for inhibiting ubiquitin specific protease 7

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United States of America Patent

PATENT NO 9546150
APP PUB NO 20140371247A1
SERIAL NO

14241923

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Abstract

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The present invention relates to quinazolin-4-one compounds of formula (I′), their process of preparation and uses thereof. These compounds are useful as selective and reversible inhibitors of ubiquitin specific proteases, particularly USP7, for treating e.g. cancer, neurodegenerative diseases, inflammatory disorders and viral infections.

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Patent Owner(s)

  • HYBRIGENICS SA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Colland, Frédéric Puiseux en France, FR 14 37
Gourdel, Marie-Edith Savigny le Temple, FR 6 117

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