Method for producing horseradish peroxidase recombinant protein using filamentous fungus
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United States of America Patent
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Jan 10, 2017
Grant Date -
May 21, 2015
app pub date -
May 30, 2013
filing date -
May 31, 2012
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Abstract
A modified polynucleotide has a different base sequence in at least one codon from a wild-type base sequence encoding a horseradish peroxidase polypeptide. The usage frequency of the modified codon of the polynucleotide corresponds to the codon usage frequencies of three filamentous fungal species in Humicola, Aspergillus, and Trichoderma. The polynucleotide is capable of expressing the polypeptide to be encoded in a filamentous fungus.
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