Method for monofluoromethylation of organic substrates to prepare biologically active organic compounds
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United States of America Patent
Stats
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Jan 10, 2017
Grant Date -
Aug 29, 2013
app pub date -
Jun 1, 2011
filing date -
Jun 1, 2010
priority date (Note) -
In Force
status (Latency Note)
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Abstract
Described herein is a process for the preparation of monofluoromethylated organic biologically active compounds using monofluoromethylated reagents. Fluticasone Propionate and Fluticasone Furoate can be prepared using, for example, S-monofluoromethyl-S-phenyl-2,3,4,5-tetramethylphenylsulfonium tetrafluoroborate as monofluoromethylating reagent instead of bromofluoromethane.
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Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
HOVIONE INTER LIMITED | 6000 LUCERNE 7 |
International Classification(s)

- 2011 Application Filing Year
- C07J Class
- 100 Applications Filed
- 57 Patents Issued To-Date
- 57 % Issued To-Date
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
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Leitao, Emilia Perpetua Tavares | Sao Marcos, PT | 7 | 5 |
# of filed Patents : 7 Total Citations : 5 |
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- 0 Citation Count
- C07J Class
- 0 % this patent is cited more than
- 8 Age
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Maintenance Fees
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11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Jul 10, 2028 |
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Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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May 02, 2017 | I | Issuance | |
Apr 12, 2017 | STCF | INFORMATION ON STATUS: PATENT GRANT | free format text: PATENTED CASE |
Sep 29, 2016 | P | Published | |
Mar 23, 2015 | F | Filing | |
Mar 23, 2015 | AS | ASSIGNMENT | free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:SHIH, PO-YUAN;CHEN, PO-YU;REEL/FRAME:039963/0026 Owner name: SINTAI OPTICAL (SHENZHEN) CO., LTD., CHINA Effective Date: Mar 23, 2015 free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:SHIH, PO-YUAN;CHEN, PO-YU;REEL/FRAME:039963/0026 Owner name: ASIA OPTICAL CO., INC., TAIWAN Effective Date: Mar 23, 2015 |
Mar 24, 2014 | PD | Priority Date |

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