Combination of immunotherapies with activators of Tie-2
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United States of America Patent
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Jan 10, 2017
Grant Date -
Feb 11, 2016
app pub date -
Aug 6, 2015
filing date -
Aug 7, 2014
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Abstract
The present invention relates to combination therapies comprising at least one activator of Tie-2 and immunotherapies that target immune checkpoints. Combination therapies of the disclosure can provide therapeutic effects not obtained with singly-administered immunotherapies. Combination therapies can be used to increase the therapeutic efficacy of an immunotherapy, to provide lower dosages of an immunotherapy being administered, to lower a toxicity of an immunotherapy, or to manage a side effect of an immunotherapy.
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