Test method and apparatus for bioreactor containers having reception sheet clamped between bioreactor container and bioreactor container compartment
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United States of America Patent
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Jan 3, 2017
Grant Date -
Jun 19, 2014
app pub date -
Jun 26, 2012
filing date -
Jun 30, 2011
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Abstract
A method for testing the integrity of a bioreactor container includes providing a bioreactor container having a fluid-tight, at least locally flexible wall and having at least one container opening and providing a test apparatus having a bioreactor container compartment and a fluid-permeable and/or structured reception sheet arranged replaceably on the bioreactor container compartment. The method continues by arranging the bioreactor container in the bioreactor container compartment so that the bioreactor container wall contacts the reception sheet in the bioreactor container compartment, connecting the container opening of the bioreactor container to a fluid source filling the bioreactor container with a fluid from the fluid source to generate a predetermined positive pressure P1 in the bioreactor container at a first time T1 and determining whether the bioreactor container is sufficiently leaktight.
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