Crystal form VII of agomelatine, preparation method and use thereof and pharmaceutical composition containing same
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United States of America Patent
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Dec 27, 2016
Grant Date -
Jan 9, 2014
app pub date -
Mar 22, 2012
filing date -
Mar 23, 2011
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Abstract
The present invention provides a new crystalline form VII of agomelatine, its method of preparation, application and pharmaceutical composition. This new crystalline form offers high purity, a stable crystalline structure and good reproducibility, while its method of production lends itself well to large scale production. In terms of stability and purity, it is superior to the numerous crystalline forms which have hitherto been reported. As a result, the crystalline form VII of the present invention possesses advantages in pharmaceutical preparation.
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