Method of screening for substances capable of promoting induction of induced pluripotent stem cells
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United States of America Patent
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Dec 20, 2016
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Jun 11, 2015
app pub date -
Sep 12, 2012
filing date -
Sep 12, 2011
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Abstract
The object of the present invention is to provide a method for screening a substance capable of promoting induction of induced pluripotent stem cells from cells derived from an individual affected by a disease for which it is impossible to produce induced pluripotent stem cells simply by introducing reprogramming genes. The present invention provides a method for screening a substance, which comprises culturing cells derived from an individual affected by a disease for which it is impossible to produce induced pluripotent stem cells simply by introducing reprogramming genes, the cells being transfected with reprogramming genes, in the presence of test substances, and selecting a test substance capable of promoting induction of induced pluripotent stem cells from the cells.
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