Glycosidase inhibitors and uses thereof
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United States of America Patent
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Dec 20, 2016
Grant Date -
Aug 6, 2015
app pub date -
Aug 29, 2013
filing date -
Aug 31, 2012
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Abstract
The invention provides compounds of Formula (I) for inhibiting gh cosidases, prodrugs of the compounds, and pharmaceutical compositions comprising the compounds or prodrugs of the compounds. The invention also provides method of treating diseases and disorders related to deficiency or over-expression of O-gh coprotein 2-acetamido-2-deoxy-β-D-glucopyranosidase (O-GlcNAcase), accumulation or deficiency of 2-acetamido-2-deoxy-β-D-glucopyranoside (O-GlcNAc).
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