Compounds and methods for modulating interaction between proteins and target nucleic acids
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United States of America Patent
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Dec 13, 2016
Grant Date -
Oct 31, 2013
app pub date -
Jun 15, 2011
filing date -
Jun 15, 2010
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Abstract
Provided herein are antisense compounds and methods for recruiting one or more non-cleaving protein to a target nucleic acid in a cell. In certain instances such recruitment of a non-cleaving protein alters the function or activity of the target nucleic acid. In certain such instances, the target nucleic acid a pre-mRNA and the recruitment of the non-cleaving protein results in a change in splicing of the pre-mRNA.
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