A4B7 peptide monomer and dimer antagonists

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Dec 13, 2016
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Feb 17, 2016
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Oct 1, 2014

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Abstract

The invention relates to peptide dimer compounds and peptide monomer compounds that potently inhibit binding of α4β7 to the mucosal addressin cell adhesion molecule (MAdCAM) in vivo, possess high selectivity against α4β1 binding, and have high stability under gastrointestinal conditions.

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PROTAGONIST THERAPEUTICS INC	7707 GATEWAY BOULEVARD NEWARK CA 94560-1160

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Inventor Name	Address	# of filed Patents	Total Citations
Bhandari, Ashok	Pleasanton, US	67	947
Liu, David	Milpitas, US	263	5445
Mattheakis, Larry C	Cupertino, US	39	878
Patel, Dinesh V	Fremont, US	71	1372
Zemede, Genet	San Jose, US	26	448

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A4B7 peptide monomer and dimer antagonists

Number of patents in Portfolio can not be more than 2000

United States of America Patent

15046325

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DATE PUBLISHED	PUBLICATION/PATENT NO.	PUBLICATION TYPE
December 13, 2016	US,9518091,B2 US9518091B2	GRANTED PATENT AS SECOND PUBLICATION
June 09, 2016	US,20160159862,A1 US20160159862A1	FIRST PUBLISHED PATENT APPLICATION

PATENT NO	9518091
SERIAL NO	15046325
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15046325

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