Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers
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United States of America Patent
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Dec 13, 2016
Grant Date -
Dec 18, 2014
app pub date -
Jun 26, 2014
filing date -
Jul 16, 2009
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Abstract
The invention relates generally to anti-angiogenesis agents and related methods of using to anti-angiogenesis agents for biomedical applications including direct monotherapy and combination therapy for treatment of an angiogenesis related condition. In an embodiment, the invention provides a class of opioid compounds and structurally related opioid derivatives exhibiting anti-VEGF activity for use in therapeutic procedures, including phototherapy. Opioid compounds and structurally related opioid derivatives of the invention may be administered alone or in combination with administration of a phototherapy agent and/or other therapeutic agent.
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