Compositions and methods for conjugating activatable antibodies

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United States of America Patent

PATENT NO 9517276
SERIAL NO

14296207

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates generally to compositions and methods for conjugating antibodies and activatable antibodies, and methods of partially reducing antibodies and/or activatable antibodies prior to conjugation, e.g., thiol-based conjugation, with an agent, e.g., a therapeutic and/or diagnostic agent.

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Patent Owner(s)

Patent OwnerAddress
CYTOMX THERAPEUTICS INC650 GATEWAY BOULEVARD #125 SOUTH SAN FRANCISCO CA 94080-7014

International Classification(s)

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  • 2014 Application Filing Year
  • A61K Class
  • 14144 Applications Filed
  • 11600 Patents Issued To-Date
  • 82.02 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2014201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Desnoyers, Luc Roland San Francisco, US 27 402
Konradi, Andrei William Burlingame, US 4 35
Liang, Tony W San Mateo, US 12 145
Lowman, Henry Bernard El Granada, US 23 448
Singh, Shweta Fremont, US 38 350

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Patent Citation Ranking

  • 16 Citation Count
  • A61K Class
  • 91.06 % this patent is cited more than
  • 9 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges6209860894426710349291291182201 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0500100015002000250030003500400045005000550060006500700075008000850090009500

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