Method of DNA sequencing by hybridisation

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United States of America Patent

PATENT NO 9512476
APP PUB NO 20130137098A1
SERIAL NO

13700109

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Abstract

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Described herein is a method for determining a nucleic acid sequence, said method comprising: a) denaturing a double-stranded nucleic acid molecule corresponding to the said nucleic acid sequence by applying a physical force to the said molecule; b) providing a single-stranded nucleic acid molecule; c) renaturing the said double stranded nucleic acid molecule in the presence of the said single-stranded nucleic acid molecule; and d) detecting a blockage of the renaturation of the double-stranded nucleic acid.

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Patent Owner(s)

Patent OwnerAddress
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)3 RUE MICHEL ANGE PARIS 75016
UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)4 PLACE JUSSIEU PARIS F-75005
ECOLE NORMALE SUPERIEURE45 RUE D'ULM PARIS 75005

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Allemand, Jean-François Arcueil, FR 6 17
Bensimon, David Paris, FR 29 377
Croquette, Vincent Antony, FR 16 81
Ding, Fang-Yuan Alhambra, US 6 29
Manosas, Maria Barcelona, ES 5 11

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