Serum-free stable transfection and production of recombinant human proteins in human cell lines

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United States of America Patent

PATENT NO 9512457
SERIAL NO

15011760

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Abstract

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The present invention relates to an improved method for the serum-free production of an immortalized human cell line stably transfected under serum-free conditions with a specific vector carrying the gene coding for the protein of interest. Furthermore the invention relates to a production cell line obtained by said method, a production method for said protein of interest utilizing said production cell line, and the specific vector carrying the gene of interest itself.

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Patent Owner(s)

Patent OwnerAddress
OCTAPHARMA AG8853 LACHEN

International Classification(s)

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  • 2016 Application Filing Year
  • C12P Class
  • 1834 Applications Filed
  • 1256 Patents Issued To-Date
  • 68.49 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances2016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ding, Haiyan Munich, DE 10 4
Schroeder, Carola Heidelberg, DE 4 3
Wegmann, Cathleen Munich, DE 4 3

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  • C12P Class
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges3040217223350209322101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8091 - 1000200400600800100012001400160018002000220024002600280030003200

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