Cell-based production of nonulosonates
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United States of America Patent
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Dec 6, 2016
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Jul 28, 2014
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Apr 20, 2010
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Abstract
The present invention relates to the cell-based production of bacterial nonulosonates and their biosynthetic precursors. Specifically, the present invention provides recombinant cells for the production of pseudaminic acid, legionaminic acid, UDP-2,4-diacetamido-2,4,6-trideoxy-□-L-altropyranose, and UDP-2,4-diacetamido-2,4,6-trideoxy-□-D-glucopyranose. Methods for producing the sugars are also provided.
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