Selective detection of amino group containing thiols
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United States of America Patent
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Nov 29, 2016
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Feb 22, 2013
filing date -
Feb 23, 2012
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Abstract
Probes for selectively detecting compounds comprising a thiol group and an amino group (“thiols”) are disclosed. Exemplary thiols include cysteine, homocysteine, and glutathione. Embodiments of the disclosed probes produce a detectable change in absorbance spectrum and/or emission spectrum when reacted with one or more thiols in solution. Methods and kits for performing the detection also are disclosed. The probes have a general formula
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