Pyridone and aza-pyridone compounds and methods of use

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United States of America Patent

PATENT NO 9505785
SERIAL NO

14059626

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Abstract

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Pyridone and aza-pyridone compounds of Formula I are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.

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GENENTECH INC1 DNA WAY SOUTH SAN FRANCISCO CA 94080-4990

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barbosa, Antonio J M Middlebury, US 5 23
Blomgren, Peter A North Branford, US 74 1440
Currie, Kevin S North Branford, US 96 2764
Krishnamoorthy, Ravi Guilderland, US 4 50
Kropf, Jeffrey E Branford, US 64 1218
Lee, Seung H Branford, US 59 1097
Mitchell, Scott A East Haven, US 75 2552
Ortwine, Daniel San Ramon, US 10 243
Schmitt, Aaron C Hamden, US 27 643
Wang, Xiaojing Foster City, US 76 956
Xu, Jianjun Madison, US 96 1261
Young, Wendy San Mateo, US 12 205
Zhang, Honglu Guilderland, US 10 99
Zhao, Zhongdong Guilford, US 45 698
Zhichkin, Pavel E Delmar, US 11 222

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